Advanced microstructure imaging · DICEtech

beyond image
resolution.Pushing what MRI can see.

MRmicro turns clinical MRI scanners into a window on tissue microstructure — quantifying cell density, neurite morphology, and tumour signature directly from a routine diffusion sequence. Compatible with 1.5 T and 3 T scanners from any vendor.

0×
Acceleration

What used to take days now takes seconds.

MRmicro fits novel diffusion microstructure models in real time on commodity hardware. No cluster, no overnight queue, no need to export patient data.

Conventional pipeline
1 day
MRmicro
10 seconds
Prostate · MRmicro

a tumour the radiologist could not see — visible in seconds.

On a routine T2 image the lesion can hide in heterogeneous tissue. VERDICT-derived microstructure maps — fitted in seconds from diffusion weighted MR sequences — quantify cell density per voxel. Toggle the layers below. Watch the lesion appear.

drag the overlay.
watch the tumour appear.

Same patient, same scanner. Twenty seconds of additional compute, a clinically actionable biomarker the radiologist can use to decide whether to biopsy — and where.

FIC 0.86
PT · 64Y · M
SER 4 · TRA · T2
FOV · 200
SLC · 18 / 32
L <
R >
A
P
Anatomical base
VERDICT overlay
fic · intracellular
Cell density · tumour signal
0.86
Overlay opacity100%
[1]
Johnston E. et al., VERDICT MRI for prostate cancer detection — INNOVATE trial. Reported risk-stratification improvement and reduction in unnecessary biopsies on the prospective cohort.
Open ↗
−91%
Reduction in unnecessary biopsies1
Fewer biopsies directly reduce complications like bleeding, infection, and sepsis.
−33%
MRI exam time without contrast*
Removing the contrast phase shortens MRI exam time by roughly one-third, freeing up scanner hours.
2-3 weeks
Reported waitlist after contrast-free workflow*
In a recent work*, avoiding contrast reduced the waitlist from 1 year to 2-3 weeks. No gadolinium injection avoids contrast-related reactions and long-term risks, creating a less invasive, less stressful pathway.
*Contrast-free workflow source10.1016/j.ejrad.2023.111186 ↗
Neuro · MRmicro

the brain, cell by cell.

MRmicro derives quantitative maps of axonal density, neurite geometry and gray-matter cytoarchitecture — biomarkers sensitive to MS, dementia and traumatic injury, more specific than conventional MRI.

DWI base01 / 05
Active viewinput DWI
SANDI

soma fraction

Cortical microstructure at millimetre scale — the first model that reads cell-body density on a clinical 3T. Sensitive to early neurodegeneration and cortical dysplasia.

intra-neurite fraction

Voxel-wise integrity of axons and dendrites across white matter. Picks up demyelination in tissue that still looks normal on FLAIR — tracks EDSS progression in MS.

extra-cellular fraction

Free water and interstitial space between cells. Rises with edema, neuroinflammation and tissue rarefaction — an early marker of neurodegeneration.

Multiple SclerosisParkinson'sEpilepsyNeurodevelopmentDiffuse Axonal Injury
Where MRmicro lives

built with radiologists. validated in hospitals.

A two-year deployment record across Italian clinical centres.

Technical partner
Siemens Healthineers
Clinical integration · since 2025
Clinical footprint
7 hospitals Italy & UK
Active deployments
Academic origin
12 years of academic research
Across worldwide leading institutions
Regulatory
CE marking
In progress · Class IIa MDR